1 (b) Methylphenidate is a controlled class II drug. It is indicated for treatment of attention deficit hyperactivity disorder (ADHD). It cannot be refilled under any circumstances.
2 (b) 1050cc. In this type of calculation first find out number of cc required for 1 day.
Morning dose
Drug ml of solution
250 mg present 5 cc of solution
1000 mg ?
1000 x 5cc / 250 = 20 cc of solution.
Evening dose
Drug ml of solution
250 mg present in 5 cc of solution
750 mg ?
750 x 5cc / 250 = 15 cc of solution.
For a 30 day supply of Valproic acid
(20 cc (am) + 15 cc (pm) ) x 30 = 1050cc.
3 (b) Glyburide and Chlorpropamide are oral sulfonylurea agents indicated for treatment of diabetes. Pharmacy technician will notify the pharmacist about duplication of therapy.
4 (d) Aspirin is a blood thinning agent indicated for prevention of heart stroke. It should be carefully prescribed with other blood thinning agents
because of risks of bleeding. Lovenox (Enoxaprine), Coumadin (Warfarin), Heparin, Plavix (Clopidrogel), Ticlid (Ticlopidine), Depakene (Valproic acid), Persantine (Dipyridamole), Mandol (Cefamandole), Cefotan (Cefotetan), Cefobid (Cefoperazone) and Moxam (Moxalactam) are agents that increase bleeding tendency in patients and should be carefully prescribed with other blood thinning agents.
5 (a) The overdose of Coumadin can be treated by administration of Vitamin K1 (Mephyton).
6 (a) Compazine (Prochlorperazine) is indicated for treatment of nausea and vomiting and therefore is classified as an anti-emetic (agent that prevent nausea and vomiting).
7 (b)
8 (b) The cost of 100 tablets of Olanzapine is $420 and therefore the cost of one tablet of Olanzapine would be $420/100 = $ 4.20.
The % mark-up on the prescription is 15%
Cost of prescription mark up on rx
$ 100 $ 15
$ 4.20 ?
15 x 4.20 / 100 = $ 0.63, therefore dispensing cost of each prescription would be
$ 4.20 + $ 0.63 = $ 4.83
The cost of 30 tablets would be $ 4.83 x 30 = $145
9 (b) 33 grams. For calculations of this type the allegation method is very useful. We want to prepare 500 gm of 0.2 % salicylic acid by mixing talc (0 %) powder with 3 % of Salicylic acid powder.
3 % salicy 0.2 (3 % sali)
0.2 %
0 % talc (no salicy) 2.8 (0% sali)
Total 3.0 (0.2 % sali)
We want to find out how many grams of 3 % salicylic acid required
Total parts of 0.2% sali Parts of 3 % sali
3 parts 0.2 parts 500 ?
500 x 0.2 / 3 = 33 grams of 3% salicylic acid required.
10 (b) Plavix (Clopidrogel) is a blood thinning agent. Agents of this class generally act by inhibiting aggregation of platelets which is thought to be the primary mechanism of blood clotting. It is indicated for prevention of heart stroke in patients with CHF.
11 (b) Asthma is characterized by increased responsiveness of trachea and bronchi to various stimuli and narrowing of airways. It is associated with shortness of breath, chest tightness, wheezing and coughing. The Beta-2 receptors stimulation generally dilates the bronchial smooth muscles and helps in controlling asthma.
Beta-2 receptors blockers generally constrict the smooth muscles of bronchi and may even aggregate asthma.
Metoprolol is a Beta-1 and Beta-2 receptor blockers indicated for treatment of hypertension and should be carefully prescribed in patient with asthma. Other choices such as Accolate and Atrovent are indicated for treatment of asthma.
12 (b) The prescription of CII controlled drugs should be dispensed with specific quantity mentioned on prescription by physician. MS-contin is a controlled II drug and therefore correct dispensing quantity would be 60.
13 (b) Prescription of controlled drugs III, IV and V cannot be refilled more than 5 times. A patient must bring a new prescription after this allowable refill is executed. Prescriptions older than 6 months require a new prescription to fill.
14 (c) Otocort otic solution is intended for ear use only. It should not be applied to eyes and therefore the auxiliary label “ For ear use only” is required.
15 (c) Tamsulosin is the generic name of Flomax. It is indicated for treatment of B.P.H. All of the rest of the choices are colony stimulator agents. They generally help in stimulation of erythrocyte and granulocytes.
16 (d) 150 cc. Lanoxin is available in 0.05 mg/ml. Patient is taking 0.25 mg per day.
Drug ml of solution
0.05 mg 1 ml
0.25 mg ?
0.25 x 1 / 0.05 = 5ml
for 30 days supply = 30 x 5cc = 150cc